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The Power of Nature Extracted by Science.

CBD is popping up all over the country as a versatile wellness supplement with an impressive array of benefits. So what is CBD, how does it work in the body, and what advantages might it provide for elderly hospice patients who want to improve their quality of life?

What is CBD?

Cannabidiol (CBD) is a non-intoxicating compound, and one of several cannabinoids found in hemp and cannabis plants.

What is hemp, how is it different from marijuana?

Hemp and marijuana are both varieties of the cannabis plant, but they differ significantly in their chemical makeup and physical characteristics. Hemp produces only trace amounts of THC (legally defined as less than 0.3%) and high concentrations of CBD, which makes it a valuable, non-intoxicating source of CBD and other helpful cannabinoids.

How does CBD work?

CBD interacts with the endocannabinoid system (ECS), a central regulatory system made up of a complex receptor network in the human body.

The ECS is like a lock-and-key system. The locks (cannabinoid receptors) are always there, waiting for the key (cannabinoids in our formulated products). When unlocked, these receptors promote wellness in the body.

Though the body has several types of receptors with which cannabinoids may interact, we know they bind to CB1 and CB2 receptors, the primary receptors in the ECS. CBD interacts primarily with CB2 receptors, which are most prominently expressed in the peripheral immune system. By interacting with the body’s ECS, CBD helps the body maintain an internal regulatory balance known as homeostasis.

Will CBD get me high?

CBD is non-intoxicating, offering wellness benefits without producing the high associated with delta-9- tetrahydrocannabinol (THC), the other prominent cannabinoid of the cannabis plant. In fact, CBD and THC have been found to have opposite effects* on regional brain function, which may explain why CBD can counteract the intoxicating effects of THC.

Is CBD addictive?

CBD is generally considered safe and non-habit-forming, even when taken in high doses. The World Health Organization** has reported that “CBD exhibits no effects indicative of any abuse or dependence potential” in humans.

What is the Entourage Effect?

The entourage effect is a term used to describe the way several cannabinoids work together to produce a greater overall effect than that of a single cannabinoid. CBD and other cannabinoids interact with our bodies through the endocannabinoid system (ECS), binding to different cannabinoid receptors in the body to help it maintain internal regulatory balance, or homeostasis. When taken together, multiple cannabinoids may produce a greater overall effect by eliciting a regulatory response at multiple receptor points.

What are Full Spectrum, Broad Spectrum, and CBD isolates? Why choose one over another?

A Full Spectrum Hemp Extract is a concentrate that preserves the entire cannabinoid profile, or spectrum of cannabinoids found in the hemp plant from which it was extracted. A broad spectrum extract may remove only one or two cannabinoids, most commonly THC. An isolate is an extraction of CBD only, resulting in a pure-CBD concentrate absent of any other cannabinoid.

For those who may be sensitive to trace amounts of THC in their bodies, CBD isolate can be a valuable wellness resource. However, when you take a CBD isolate, you’re only getting the benefits of a single cannabinoid. Taking a Full or Broad Spectrum extract, like the ones in MyRemedeMD tablets, allows the patient to take advantage of the entourage effect and experience the greater impact of the hemp plant’s natural cannabinoid profile.

How should I dose my CBD?

As is the case with most natural supplements, everyone’s body absorbs, metabolizes, and responds to CBD differently. Finding the optimal dosing range for the particular benefits you’re seeking is typically best achieved by starting with smaller daily doses and working your way up over two or three weeks.

CBD is also a biphasic compound, which means it may elicit different reactions at different concentration levels. To help you conveniently find the most effective dosage, MyRemedeMD offers tablets in 10 and 25mg tablets. An elderly patient taking CBD as a natural sleep aid may want to start with a 25mg tablet before bed, while a patient experiencing general fatigue or basic aches and pains may want to begin with 10mg during the day.

What time should I take CBD?

When to take CBD depends largely on what you’re using it for. A patient taking CBD to help with sleep may want a higher dose before bed, while a patient who wants to feel calm and alert throughout the day may want to experiment with a 10mg tablet in the morning or at lunch. Similar to CBD dosage and concentration, the time of day in which a patient takes CBD should be tailored to their needs.

Does CBD make you sleepy?

CBD won’t necessarily make you sleepy, but it may calm and relax you so it’s easier to fall asleep, especially in high doses.

Are there other side effects?

Studies have indicated that even the highest doses of CBD are safe*** for human consumption. Still, more research is needed to make clear distinctions about CBD side effects. CBD may also interact with or alter the effects of other medications, so patients with unique conditions or medications should consult with a doctor before taking CBD as a regular supplement.

Why MyRemedeMD tablet?

From cultivation to harvest to extraction to formulation, we control every aspect of every stage of production to make sure our tablets contain the things we want in our bodies, and none of the things we don’t. The MyRemedeMD tablet is designed for time release absorption, which allows for a more controlled dosage and steadier delivery of effect. There’s also no need to take our tablet with food, so patients can schedule doses at their convenience.

Sources

*Bhattacharyya, Sagnik, et al. “Opposite Effects of Δ-9-Tetrahydrocannabinol and Cannabidiol on Human Brain Function and Psychopathology.” Neuropsychopharmacology, vol. 35, no. 3, 18 Nov. 2009, pp. 764–774., doi:10.1038/npp.2009.184.

**CANNABIDIOL (CBD) Pre-Review Report. Agenda Item 5.2, Expert Committee on Drug Dependence, Thirty-ninth Meeting. Geneva, 6-10 November 2017

***Bergamaschi, Mateus Machado, et al. “Safety and Side Effects of Cannabidiol, a Cannabis Sativa Constituent.” Current Drug Safety, vol. 6, no. 4, 1 Sept. 2011, pp. 237–249., doi:10.2174/157488611798280924.

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